Griffith’s experiment
Griffith’s experiment
- Rough strain of Streptococcus was injected into the mouse. The mouse lived.
- Smooth strain of Streptococcus was injected into the mouse. The mouse died.
- When heat-killed smooth strain of Streptococcus was injected into the mouse, the mouse lived.
- In the last set of experiments, rough strain and heat-killed smooth strain were injected into the mouse. The mouse died.
This proved that there was some substance present in heat-killed S strain that was converting or transforming the rough strain into virulent strain, leading to the death of the mouse. This transforming substance was later found to be DNA.
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